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Travelers in the Midwest, Great Lakes and Appalachians are dealing with major weather-related headaches as Winter Storm Petros continues to dump snow and produce heavy winds throughout the day, and projected into Thursday.

According to Weather.com, the National Weather Service has issued blizzard warnings from central Illinois to northwest Indiana, and has issued winter weather warnings and advisories from the Ozarks to Lower Michigan.

While areas like New England will see some snow and ice related to Winter Storm Petros, most regions along the East Coast will instead be subjected to heavy rain throughout Wednesday and Thursday.

READ MORE: Travel Agents Share Tips for Dealing With Winter Storm Delays

Winter Storm Petros was a result of a low-pressure system that is also causing havoc in the south, as severe thunderstorms and deadly tornadoes have been reported in Florida, along the Gulf Coast and in the Mid-Atlantic region.

Ground travel in the Midwest will be difficult thanks to the accumulations of snow and ice, but flying won’t be much better. With Chicago being hit hard by the winter storm, O'Hare International Airport and Chicago Midway International Airport have cancelled over 470 combined flights, as of 9:45 a.m. ET, according to FlightAware.com.

Weather reports indicate Winter Storm Petros will continue wreaking havoc on Wednesday, before starting to dissipate overnight and coming to a complete stop on Thursday. In the meantime, travelers should be prepared for delays and cancellations.

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