The Caribbean was one of the first regions to reopen to tourism amid the COVID-19 pandemic last year and many cruise lines have their sights set on these inviting island destinations as they resume operations from the U.S.
Several notable ships will cruise the Caribbean this summer but passengers sailing out of the U.S. will also have options in places like Alaska, Bermuda, Mexico and Central America. Travelers will also continue to have domestic options like Mississippi River sailings and other iconic waterways on river cruise lines operating smaller ships like American Cruise Lines, Victory Cruise Lines, and American Queen Steamboat Company.